How to be a male without the Y chromosome

Chromosomal location of the sex-related gene AMH (arrowheads) in male T. osimensis. Chromosomes are double-stained with different fluorescent substances (red and blue) for the precise gene mapping.Credit: Otake T. and Kuroiwa A. Molecular mechanism of male differentiation is conserved in … Continue reading

Mice born from ‘tricked’ eggs

Eggs can be ‘tricked’ into developing into an embryo without fertilisation, but the resulting embryos, called parthenogenotes, die after a few days because key developmental processes requiring input from sperm don’t happen. However, scientists from the Department of Biology & … Continue reading

Why do aged muscles heal slowly?

As we age, the function and regenerative abilities of skeletal muscles deteriorate, which means it is difficult for the elderly to recover from injury or surgery. New work from Carnegie’s Michelle Rozo, Liangji Li, and Chen-Ming Fan demonstrates that a … Continue reading

Seeing RNA at the nanoscale

MIT researchers have developed a new way to image proteins and RNA inside neurons of intact brain tissue.Image: Yosuke Bando, Fei Chen, Dawen Cai, Ed Boyden, and Young Gyu Cells contain thousands of messenger RNA molecules, which carry copies of … Continue reading

Solving a mitochondrial mystery

Credit: University of Colorado at Boulder When it comes to mitochondrial inheritance, maternal genes rule the day at the expense of paternal ones. But why? A new study, published today in the journal Science and led by University of Colorado … Continue reading